Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00363"

Predicate	Value (sorted: default)
rdfs:label	"Clozapine"
rdf:type	drugbank:drugs
drugbank:description	"A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent. [PubChem]"
drugbank:drugCategory	drugcategory:Antipsychotic Agents drugcategory:GABA Antagonists drugcategory:Serotonin Antagonists
drugbank:interactsWith	drug:Fluvoxamine drug:Lorazepam drug:Tramadol drug:Erythromycin drug:Caffeine drug:Trospium drug:Citalopram drug:Temazepam drug:Phenytoin drug:Clobazam drug:Tacrine drug:Alprazolam drug:Triprolidine drug:Fluoxetine drug:Chlordiazepoxide drug:Cimetidine drug:Haloperidol drug:Ritonavir drug:Mephenytoin drug:Ciprofloxacin drug:Lamotrigine drug:Carbamazepine drug:Rifabutin drug:Clorazepate drug:Trimethobenzamide drug:Galantamine drug:Tamoxifen drug:Midazolam drug:Flurazepam drug:Tamsulosin drug:Thiabendazole drug:Modafinil drug:Ethotoin drug:Halazepam drug:Diazepam drug:Oxazepam drug:Donepezil drug:Triazolam drug:Rivastigmine drug:Rifampicin drug:Norfloxacin drug:Clonazepam drug:Sertraline drug:Estazolam drug:Paclitaxel drug:Fosphenytoin drug:Josamycin drug:Flunitrazepam drug:Dihydrocodeine drug:Bromazepam drug:Ketazolam drug:Prazepam drug:Quazepam drug:Cinolazepam drug:Nitrazepam drug:Tetrabenazine drug:ado-trastuzumab emtansine drug:Vilazodone drug:Tofacitinib
owl:sameAs	drug:APRD00470 drug:BE0002363 drug:BE0002433 drug:BE0002638 drug:BE0002793 drug:BE0003536 drug:BE0003544 drug:BE0003606 drug:Fluvoxamine drug:Lorazepam drug:Tramadol drug:Erythromycin drug:Caffeine drug:Trospium drug:Citalopram drug:Temazepam drug:Phenytoin drug:Clobazam drug:Clozapine drug:Tacrine drug:Alprazolam drug:Triprolidine drug:Fluoxetine drug:Chlordiazepoxide drug:Cimetidine drug:Haloperidol drug:Ritonavir drug:Mephenytoin drug:Ciprofloxacin drug:Lamotrigine drug:Carbamazepine drug:Rifabutin drug:Clorazepate drug:Trimethobenzamide drug:Galantamine drug:Tamoxifen drug:Midazolam drug:Flurazepam drug:Tamsulosin drug:Thiabendazole drug:Modafinil drug:Ethotoin drug:Halazepam drug:Diazepam drug:Oxazepam drug:Donepezil drug:Triazolam drug:Rivastigmine drug:Rifampicin drug:Norfloxacin drug:Clonazepam drug:Sertraline drug:Estazolam drug:Paclitaxel drug:Fosphenytoin drug:Josamycin drug:Flunitrazepam drug:Dihydrocodeine drug:Bromazepam drug:Ketazolam drug:Prazepam drug:Quazepam drug:Cinolazepam drug:Nitrazepam drug:Tetrabenazine drug:ado-trastuzumab emtansine drug:Vilazodone drug:Tofacitinib drug:DBMET00100 drug:DBMET00101 drug:DBMET00102

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines2/drugbank_small.nt

The resource appears as object in 119 triples

Context graph