Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00530"

Predicate	Value (sorted: default)
rdfs:label	"Erlotinib"
rdf:type	drugbank:drugs
drugbank:description	"Erlotinib hydrochloride (trade name Tarceva, Genentech/OSIP, originally coded as OSI-774) is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. Similar to gefitinib, erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase. It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. Erlotinib has recently been shown to be a potent inhibitor of JAK2V617F activity. JAK2V617F is a mutant of tyrosine kinase JAK2, is found in most patients with polycythemia vera (PV) and a substantial proportion of patients with idiopathic myelofibrosis or essential thrombocythemia. The study suggests that erlotinib may be used for treatment of JAK2V617F-positive PV and other myeloproliferative disorders."
drugbank:drugCategory	drugcategory:Protein Kinase Inhibitors
drugbank:interactsWith	drug:Trastuzumab drug:Erythromycin drug:Nelfinavir drug:Indinavir drug:Ritonavir drug:Voriconazole drug:Rifabutin drug:Telithromycin drug:Ketoconazole drug:Rifampicin drug:Atazanavir drug:Nefazodone drug:Itraconazole drug:Rifapentine drug:Clarithromycin drug:Saquinavir drug:St. John's Wort drug:Troleandomycin
owl:sameAs	drug:APRD00951 drug:Trastuzumab drug:Erythromycin drug:Nelfinavir drug:Indinavir drug:Ritonavir drug:Erlotinib drug:Voriconazole drug:Rifabutin drug:Telithromycin drug:Ketoconazole drug:Rifampicin drug:Atazanavir drug:Nefazodone drug:Itraconazole drug:Rifapentine drug:Clarithromycin drug:Saquinavir drug:St. John's Wort drug:Troleandomycin drug:DBSALT000064

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines2/drugbank_small.nt

The resource appears as object in 37 triples

Context graph