Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00641"

Predicate	Value (sorted: default)
rdfs:label	"Simvastatin"
rdf:type	drugbank:drugs
drugbank:description	"Simvastatin is a lipid-lowering agent that is derived synthetically from the fermentation of Aspergillus terreus. It is a potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (hydroxymethylglutaryl COA reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL receptors, it increases breakdown of LDL cholesterol. [PubChem]"
drugbank:drugCategory	drugcategory:Anticholesteremic Agents drugcategory:Hydroxymethylglutaryl-CoA Reductase Inhibitors drugcategory:Hypolipidemic Agents
drugbank:interactsWith	drug:Cyclosporine drug:Fluconazole drug:Erythromycin drug:Nelfinavir drug:Nevirapine drug:Ranolazine drug:Diltiazem drug:Bosentan drug:Carbamazepine drug:Voriconazole drug:Rifabutin drug:Imatinib drug:Efavirenz drug:Verapamil drug:Amprenavir drug:Delavirdine drug:Tipranavir drug:Telithromycin drug:Ketoconazole drug:Fenofibrate drug:Rifampicin drug:Atazanavir drug:Amiodarone drug:Nefazodone drug:Itraconazole drug:Clarithromycin drug:Gemfibrozil drug:Fosamprenavir drug:Quinupristin drug:Colchicine drug:Fusidic Acid drug:Dronedarone drug:Telaprevir drug:Tocilizumab drug:Saxagliptin drug:Etravirine drug:Pazopanib drug:Ticagrelor drug:Lomitapide
owl:sameAs	drug:APRD00104 drug:BE0002638 drug:Cyclosporine drug:Cholecalciferol drug:Fluconazole drug:Erythromycin drug:Nelfinavir drug:Nevirapine drug:Ranolazine drug:Diltiazem drug:Bosentan drug:Carbamazepine drug:Voriconazole drug:Rifabutin drug:Imatinib drug:Efavirenz drug:Simvastatin drug:Verapamil drug:Amprenavir drug:Delavirdine drug:Tipranavir drug:Telithromycin drug:Ketoconazole drug:Fenofibrate drug:Rifampicin drug:Atazanavir drug:Amiodarone drug:Nefazodone drug:Itraconazole drug:Clarithromycin drug:Gemfibrozil drug:Fosamprenavir drug:Quinupristin drug:Colchicine drug:Iron drug:Geranyl Diphosphate drug:Fusidic Acid drug:Cholesterol drug:Dronedarone drug:Telaprevir drug:Tocilizumab drug:Saxagliptin drug:Etravirine drug:Pazopanib drug:Ticagrelor drug:Lomitapide drug:DBMET00388

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines2/drugbank_small.nt

The resource appears as object in 83 triples

Context graph