Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00796"

PredicateValue (sorted: default)
rdfs:label
"Candesartan"
rdf:type
drugbank:drugs
drugbank:description
"Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease. "
drugbank:drugCategory
drugcategory:Angiotensin II Type 1 Receptor Blockers
drugcategory:Angiotensin Receptor Antagonists
drugcategory:Antihypertensive Agents
drugbank:interactsWith
drug:Treprostinil
drug:Triamterene
drug:Spironolactone
drug:Trandolapril
drug:Amiloride
drug:Tobramycin
drug:Potassium
drug:Lithium
drug:Drospirenone
owl:sameAs
drug:APRD00420
drug:BE0000017
drug:BE0002793
drug:BE0003677
drug:Treprostinil
drug:Triamterene
drug:Spironolactone
drug:Trandolapril
drug:Amiloride
drug:Tobramycin
drug:Candesartan
drug:Potassium
drug:Lithium
drug:Drospirenone
drug:Zinc
drug:DBMET00005
drug:DBMET00006
drug:DBMET00007

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines2/drugbank_small.nt

The resource appears as object in 20 triples

Context graph