Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00926"
Predicate | Value (sorted: default) |
---|---|
rdfs:label |
"Etretinate"
|
rdf:type | |
drugbank:description |
"Etretinate is a medication used to treat severe psoriasis. It is a synthetic aromatic retinoid. The mechanism of action of etretinate is still incompletely understood although, like retinoic acid, it is thought to interfere with the terminal differentiation of keratinocytes. It is thought to bind to the retinoic acid receptors. Etretinate is also believed to enhance the binding of cAMP to the regulatory RI subunit of cAMP dependent protein kinases. It was removed from the United States market in 1998 and the Canadian market in 1996 as a psoriasis medication, due to the high risk of birth defects. Etretinate is now used to treat T-cell lymphomas. It also appears to inhibit NADH oxidase activity."
|
drugbank:interactsWith | |
owl:sameAs |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines2/drugbank_small.nt
The resource appears as object in 16 triples