Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB01194"

Predicate	Value (sorted: default)
rdfs:label	"Brinzolamide"
rdf:type	drugbank:drugs
drugbank:description	"Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor. Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. It catalyzes the reversible reaction involving the hydration of carbon dioxide and the dehydration of carbonic acid. In humans, carbonic anhydrase exists as a number of isoenzymes, the most active being carbonic anhydrase II (CA-II). Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. The result is a reduction in intraocular pressure. Brinzolamide is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma."
drugbank:drugCategory	drugcategory:Anti-glaucoma Agents drugcategory:Ophthalmics
drugbank:interactsWith	drug:Topiramate drug:Methazolamide drug:Acetazolamide drug:Dorzolamide drug:Zonisamide drug:Diclofenamide
owl:sameAs	drug:APRD00475 drug:Topiramate drug:Methazolamide drug:Acetazolamide drug:Dorzolamide drug:Zonisamide drug:Diclofenamide

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines2/drugbank_small.nt

The resource appears as object in 12 triples

Context graph