Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB01194"

Predicate	Value (sorted: none)
owl:sameAs	drug:Topiramate
rdf:type	drugbank:drugs
owl:sameAs	drug:Acetazolamide
drugbank:interactsWith	drug:Zonisamide
drugbank:interactsWith	drug:Dorzolamide
owl:sameAs	drug:Dorzolamide
rdfs:label	"Brinzolamide"
drugbank:interactsWith	drug:Diclofenamide
drugbank:interactsWith	drug:Acetazolamide
owl:sameAs	drug:Zonisamide
owl:sameAs	drug:APRD00475
drugbank:drugCategory	drugcategory:Anti-glaucoma Agents
owl:sameAs	drug:Diclofenamide
drugbank:description	"Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor. Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. It catalyzes the reversible reaction involving the hydration of carbon dioxide and the dehydration of carbonic acid. In humans, carbonic anhydrase exists as a number of isoenzymes, the most active being carbonic anhydrase II (CA-II). Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. The result is a reduction in intraocular pressure. Brinzolamide is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma."
drugbank:interactsWith	drug:Methazolamide
owl:sameAs	drug:Methazolamide
drugbank:interactsWith	drug:Topiramate
drugbank:drugCategory	drugcategory:Ophthalmics

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines2/drugbank_small.nt

The resource appears as object in 12 triples

Context graph