Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB01267"

PredicateValue (sorted: default)
rdfs:label
"Paliperidone"
rdf:type
drugbank:drugs
drugbank:description
"Paliperidone is the primary active metabolite of the older antipsychotic risperidone. While its specific mechanism of action is unknown, it is believed that paliperidone and risperidone act via similar if not the same pathways. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism. Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic receptors, which may explain some of the other effects of the drug. Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006."
drugbank:drugCategory
drugcategory:Antipsychotic Agents
drugbank:interactsWith
drug:Ropinirole
drug:Tacrine
drug:Pramipexole
drug:Triprolidine
drug:Apomorphine
drug:Risperidone
drug:Amantadine
drug:Bromocriptine
drug:Metoclopramide
drug:L-DOPA
drug:Methotrimeprazine
drug:Tetrabenazine
owl:sameAs
drug:Ropinirole
drug:Tacrine
drug:Pramipexole
drug:Triprolidine
drug:Apomorphine
drug:Risperidone
drug:Amantadine
drug:Bromocriptine
drug:Metoclopramide
drug:L-DOPA
drug:Methotrimeprazine
drug:Tetrabenazine

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines2/drugbank_small.nt

The resource appears as object in 24 triples

Context graph