Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB01382"

PredicateValue (sorted: default)
rdfs:label
"Glycodiazine"
rdf:type
drugbank:drugs
drugbank:description
"Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral tissues to insulin. Glycodiazine likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the membrane. Membrane depolarization stimulates calcium ion influx through voltage-sensitive calcium channels. This increase in intracellular calcium ion concentration induces the secretion of insulin. It is used for the concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus."
drugbank:interactsWith
drug:Esmolol
drug:Metoprolol
drug:Atenolol
drug:Timolol
drug:Chloramphenicol
drug:Propranolol
drug:Labetalol
drug:Bisoprolol
drug:Clofibrate
drug:Phenylbutazone
drug:Acetylsalicylic acid
drug:Pindolol
drug:Rifampicin
drug:Carvedilol
drug:Nadolol
drug:Oxprenolol
owl:sameAs
drug:Esmolol
drug:Metoprolol
drug:Atenolol
drug:Timolol
drug:Chloramphenicol
drug:Propranolol
drug:Labetalol
drug:Bisoprolol
drug:Clofibrate
drug:Phenylbutazone
drug:Acetylsalicylic acid
drug:Pindolol
drug:Rifampicin
drug:Carvedilol
drug:Nadolol
drug:Oxprenolol

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines2/drugbank_small.nt

The resource appears as object in 32 triples

Context graph