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Predicate	Value (sorted: default)
rdfs:label	"1-Methoxy-2-[2-(2-Methoxy-Ethoxy]-Ethane"
rdf:type	drugbank:drugs
drugbank:description	" experimental This compound belongs to the polyamines. These are compounds containing more than one amine group. Polyamines Organic Compounds Organonitrogen Compounds Amines Polyamines Ethers logP -0.09 ALOGPS logS -1 ALOGPS Water Solubility 1.67e+01 g/l ALOGPS logP -0.016 ChemAxon IUPAC Name 2,5,8,11-tetraoxadodecane ChemAxon Traditional IUPAC Name triglyme ChemAxon Molecular Weight 178.2261 ChemAxon Monoisotopic Weight 178.120509064 ChemAxon SMILES COCCOCCOCCOC ChemAxon Molecular Formula C8H18O4 ChemAxon InChI InChI=1S/C8H18O4/c1-9-3-5-11-7-8-12-6-4-10-2/h3-8H2,1-2H3 ChemAxon InChIKey InChIKey=YFNKIDBQEZZDLK-UHFFFAOYSA-N ChemAxon Polar Surface Area (PSA) 36.92 ChemAxon Refractivity 46.14 ChemAxon Polarizability 20.81 ChemAxon Rotatable Bond Count 9 ChemAxon H Bond Acceptor Count 4 ChemAxon H Bond Donor Count 0 ChemAxon pKa (strongest basic) -3.5 ChemAxon Physiological Charge 0 ChemAxon Number of Rings 0 ChemAxon Bioavailability 1 ChemAxon Rule of Five true ChemAxon Ghose Filter true ChemAxon ChEBI 44842 PubChem Compound 8189 PubChem Substance 46505275 ChemSpider 13835222 PDB PG5 BE0001484 Outer-membrane lipoprotein LolB Shigella flexneri # Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284 # Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423 unknown Outer-membrane lipoprotein LolB Cell wall/membrane/envelope biogenesis Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein lolB Cell outer membrane; lipid-anchor None 9.19 23551.0 Shigella flexneri GenBank Gene Database AE005674 UniProtKB P61322 UniProt Accession LOLB_SHIFL Outer-membrane lipoprotein lolB precursor >Outer-membrane lipoprotein lolB precursor MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQDVRNLNQYQTRGAFAY ISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEE MIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEITYSQNGKNWKVVYGGYDTKT QPAMPANMELTDGGQRIKLKMDNWIVK >624 bp TTATTTCACTATCCAGTTATCCATTTTTAACTTGATGCGTTGACCACCGTCGGTGAGTTC CATATTGGCTGGCATCGCAGGTTGCGTTTTGGTGTCATAACCACCATAAACAACCTTCCA GTTTTTGCCATTCTGGCTGTAGGTAATTTCGCTCAGGCGGTACTGGTCGTCCAGTTTGTA GTCGGTTGCATCACCCGGTAAACCTAAAATCCACTGGCGCAAGCTGTTGAGCGGAATTGG CATTCCGGTCAATTTGCCAATCATCTCTTCGGCGTCATCGGCGGTATAACGCTGACCTTT ATTGTCGACCAACTGCACGTTACCCGGTTGAGCATTCAGCTCCAGTTCCGTGCTGCCCAA TGGGTTAGTGAGCAGCAGACGGTAGCGATCCTGGCCGGTTTGCTGCCAGAAAAAGCGGGC GTACACTTTTTGTTGGTCAGAAATATAAGCGAACGCGCCGCGAGTCTGATACTGATTAAG ATTGCGCACGTCTTGCTGATGCTGACGCCATTGTGGCGAATCCGGGCTTTTGCCAGGACC TTTGGGCGTGGTAACGGAACAGGCAGTGAGCACAAGAGCAGCCAGCGGTAGCAGGCGGAT AAGACGAAAATCGGGCAGGGGCAT PF03550 LolB component outer membrane component outer membrane (sensu Gram-negative Bacteria) component cell component membrane process physiological process process cellular physiological process process transport process protein transport BE0004295 Profilin-2 Human # Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235 unknown Profilin-2 Involved in actin binding Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG PFN2 3q25.1-q25.2 Cytoplasm, cytoskeleton None 7.04 15046.2 Human HUGO Gene Nomenclature Committee (HGNC) GNC:8882 GeneCards PFN2 GenBank Gene Database L10678 GenBank Protein Database 190388 UniProtKB P35080 UniProt Accession PROF2_HUMAN Profilin II >Profilin-2 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH GGGLNKKAYSMAKYLRDSGF >423 bp ATGGCCGGTTGGCAGAGCTACGTGGATAACCTGATGTGCGATGGCTGCTGCCAGGAGGCC GCCATTGTCGGCTACTGCGACGCCAAATACGTCTGGGCAGCCACGGCCGGGGGCGTCTTT CAGAGCATTACGCCAATAGAAATAGATATGATTGTAGGAAAAGACCGGGAAGGTTTCTTT ACCAACGGTTTGACTCTTGGCGCGAAGAAATGCTCAGTGATCAGAGATAGTCTATACGTC GATGGTGACTGCACAATGGACATCCGGACAAAGAGTCAAGGTGGGGAGCCAACATACAAT GTGGCTGTCGGCAGAGCTGGTAGAGCATTGGTTATAGTCATGGGAAAGGAAGGTGTCCAC GGAGGCACACTTAACAAGAAAGCATATGAACTCGCTTTATACCTGAGGAGGTCTGATGTG TAA PF00235 Profilin component organelle component non-membrane-bound organelle component intracellular non-membrane-bound organelle component cytoskeleton component actin cytoskeleton function binding function cytoskeletal protein binding function actin binding function protein binding process organelle organization and biogenesis process cytoskeleton organization and biogenesis process physiological process process cellular physiological process process cell organization and biogenesis process actin filament-based process process actin cytoskeleton organization and biogenesis BE0004296 Outer-membrane lipoprotein LolB Escherichia coli (strain K12) # Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235 unknown Outer-membrane lipoprotein LolB Cell wall/membrane/envelope biogenesis Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein. Essential for E.coli viability lolB Cell outer membrane None 9.19 23550.6 Escherichia coli (strain K12) GeneCards lolB GenBank Gene Database M77237 GenBank Protein Database 290462 UniProtKB P61320 UniProt Accession LOLB_ECOLI >Outer-membrane lipoprotein lolB MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQDVRNLNQYQTRGAFAY ISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEE MIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEITYSQNGKNWKVVYGGYDTKT QPAMPANMELTDGGQRIKLKMDNWIVK >69 bp ATGTCTGCGGGAAATAATACCAACGTTGATAGGGTTAGTCTGCTTGCATCATACATACAG GATGCGTAA PF03550 LolB component cell component membrane component outer membrane component outer membrane (sensu Gram-negative Bacteria) process cellular physiological process process transport process protein transport process physiological process BE0004297 Uncharacterized protein Agrobacterium tumefaciens (strain C58 / ATCC 33970) # Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235 unknown Uncharacterized protein Translation, ribosomal structure and biogenesis AGR_C_2535 None 5.15 16232.6 Agrobacterium tumefaciens (strain C58 / ATCC 33970) GenBank Gene Database AE007869 GenBank Protein Database 15154859 UniProtKB A9CJ63 UniProt Accession A9CJ63_AGRT5 >Putative uncharacterized protein MSDVIEGRLKELGFTLPVAAAPAANYVPFTISGNLLYVSGQLPMESGKIAVTGLVGRDVD VASAQRAAELCAVNILAQVKAALNGDLSKIRRVIKLNGFVASVPEFVEQHLVINGASNLI ATVLGEPGRHARAAVGMASLPFNASVEIDAIVEIDV >822 bp GTGGAGAACAAAAAAAGCTTCTTCCATCTGCACCTGATTTCGGACTCGACGGGAGAGACT CTGATGTCGGCCGGCCGCGCCGTCTCGGCGCAGTTTCATACATCCATGCCGGTGGAACAT GTCTATCCGATGATCCGCAACCAGAAGCAGCTCGCGCAGGTCATCGATCTCATCGACAAG GAGCCCGGCATTGTTCTTTATACAATCGTTGATCAGCAGCTGGCGGAATTCCTGGATCTG CGCTGCCATGCGATTGGCGTGCCCTGCGTCAACGTTCTCGAACCGATCATCGGCATTTTC CAGACCTATCTCGGCGCGCCGTCCAGGCGGCGGGTGGGTGCGCAACACGCGCTGAATGCC GATTATTTCGCGCGGATCGAAGCACTCAATTTCGCCATGGACCATGATGACGGGCAGATG CCGGAGACCTATGACGATGCGGATGTCGTCATCATCGGCATCAGCCGCACGTCGAAAACA CCAACCAGCATCTATCTTGCTAACAGGGGCATAAAGACTGCCAATATCCCGGTCGTTCCC AATGTGCCTTTGCCCGAAAGCCTATATGCCGCGACCCGGCCGTTGATCGTCGGTCTCGTC GCGACATCGGATCGCATATCGCAGGTTCGTGAGAACAGGGATCTGGGTACAACCGGCGGA TTTGACGGTGGCCGTTACACGGATCGCGCCACCATCATGGAAGAGCTGAAATATGCGCGT GCGCTCTGCGCCCGCAACAATTGGCCGCTGATCGACGTCACACGCCGTTCCATCGAGGAA ACGGCCGCGGCGATCCTTGCCCTGCGCCCGAGGACGCGATAA PF01042 Ribonuc_L-PSP BE0004298 Serine acetyltransferase Yersinia pestis # Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235 unknown Serine acetyltransferase Amino acid transport and metabolism cysE None 6.51 29172.2 Yersinia pestis GeneCards cysE GenBank Gene Database AL590842 GenBank Protein Database 115345833 UniProtKB Q0WKM4 UniProt Accession Q0WKM4_YERPE >Serine acetyltransferase MSSEELEQVWSNIKSEARALAECEPMLASFFHATLLKHENLGSALSYILANKLANPIMPA IAIREVVEEAYRSDAHMIVSAARDILAVRLRDPAVDKYSTPLLYLKGFHALQAYRIGHWL WAQDRKALAIYLQNQVSVAFGVDIHPAATIGCGIMLDHATGIVIGETAVVENDVSILQSV TLGGTGKTSGDRHPKIREGVMIGAGAKILGNIEVGRGAKIGAGSVVLQSVPAHTTAAGVP ARIVGKPESDKPSLDMDQHFNGSIQGFEYGDGI >993 bp ATGAAAAAACAATTTATCCAAAAACAACAACAAATCAGCTTCGTAAAATCATTCTTTTCC CGCCAATTAGAGCAACAACTTGGCTTGATCGAAGTCCAGGCTCCTATTTTGAGCCGTGTG GGTGATGGAACCCAAGATAACCTTTCTGGTTCTGAGAAAGCGGTACAGGTAAAAGTTAAG TCATTGCCGGATTCAACTTTTGAAGTTGTACATTCATTAGCGAAGTGGAAACGTAAAACC TTAGGGCGTTTTGATTTTGGTGCTGACCAAGGGGTGTATACCCATATGAAAGCATTGCGC CCAGATGAAGATCGCCTGAGTGCTATTCATTCTGTATATGTAGATCAGTGGGATTGGGAA CGGGTTATGGGGGACGGTGAACGTAACCTGGCTTACCTGAAATCGACTGTTAACAAGATT TATGCAGCGATTAAAGAAACTGAAGCGGCGATCAGTGCTGAGTTTGGTGTGAAGCCTTTC CTGCCGGATCATATTCAGTTTATCCACAGTGAAAGCCTGCGGGCCAGATTCCCTGATTTA GATGCTAAAGGCCGTGAACGTGCAATTGCCAAAGAGTTAGGTGCTGTCTTCCTTATAGGG ATTGGTGGCAAATTGGCAGATGGTCAATCCCATGATGTTCGTGCGCCAGATTATGATGAT TGGACCTCTCCGAGTGCGGAAGGTTTCTCTGGATTAAACGGCGACATTATTGTCTGGAAC CCAATATTGGAAGATGCCTTTGAGATATCTTCTATGGGAATTCGTGTTGATGCCGAAGCT CTTAAGCGTCAGTTAGCCCTGACTGGCGATGAAGACCGCTTGGAACTGGAATGGCATCAA TCACTGTTGCGCGGTGAAATGCCACAAACTATCGGGGGAGGTATTGGTCAGTCCCGCTTA GTGATGTTATTGCTGCAGAAACAACATATTGGTCAGGTGCAATGTGGTGTTTGGGGCCCT GAAATCAGCGAGAAAGTTGATGGCCTGCTGTAA PF00132 Hexapep PF06426 SATase_N component cell component intracellular component cytoplasm function O-acyltransferase activity function transferase activity function serine O-acyltransferase activity function serine O-acetyltransferase activity function transferase activity, transferring acyl groups function catalytic activity function transferase activity, transferring groups other than amino-acyl groups function acyltransferase activity process amino acid and derivative metabolism process serine family amino acid metabolism process physiological process process metabolism process cellular metabolism process L-serine metabolism process amino acid metabolism process cysteine biosynthesis from serine BE0000839 Tyrosine-protein kinase Fyn Human # Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235 unknown Tyrosine-protein kinase Fyn Involved in protein kinase activity Implicated in the control of cell growth FYN 6q21 Cell membrane. Present and active in lipid rafts None 6.65 60631.0 Human HUGO Gene Nomenclature Committee (HGNC) HGNC:4037 GenAtlas FYN GeneCards FYN GenBank Gene Database M14333 GenBank Protein Database 338228 UniProtKB P06241 UniProt Accession FYN_HUMAN EC 2.7.10.2 p59-Fyn Protooncogene Syn SLK >Proto-oncogene tyrosine-protein kinase Fyn GCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGL TVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWE ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCR LVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTL KPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRA LKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYT ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER GYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPGENL >1614 bp ATGGGCTGTGTGCAATGTAAGGATAAAGAAGCAACAAAACTGACGGAGGAGAGGGACGGC AGCCTGAACCAGAGCTCTGGGTACCGCTATGGCACAGACCCCACCCCTCAGCACTACCCC AGCTTCGGTGTGACCTCCATCCCCAACTACAACAACTTCCACGCAGCCGGGGGCCAAGGA CTCACCGTCTTTGGAGGTGTGAACTCTTCGTCTCATACGGGGACCTTGCGTACGAGAGGA GGAACAGGAGTGACACTCTTTGTGGCCCTTTATGACTATGAAGCACGGACAGAAGATGAC CTGAGTTTTCACAAAGGAGAAAAATTTCAAATATTGAACAGCTCGGAAGGAGATTGGTGG GAAGCCCGCTCCTTGACAACTGGAGAGACAGGTTACATTCCCAGCAATTATGTGGCTCCA GTTGACTCTATCCAGGCAGAAGAGTGGTACTTTGGAAAACTTGGCCGAAAAGATGCTGAG CGACAGCTATTGTCCTTTGGAAACCCAAGAGGTACCTTTCTTATCCGCGAGAGTGAAACC ACCAAAGGGTCCTATTCACTTTCTATCCGTGATTGGGATGATATGAAAGGAGACCATGTC AAACATTATAAAATTCGCAAACTTGACAATGGTGGATACTACATTACCACCCGGGCCCAG TTTGAAACACTTCAGCAGCTTGTACAACATTACTCAGAGAGAGCTGCAGGTCTCTGCTGC CGCCTAGTAGTTCCCTGTCACAAAGGGATGCCAAGGCTTACCGATCTGTCTGTCAAAACC AAAGATGTCTGGGAAATCCCTCGAGAATCCCTGCAGTTGATCAAGAGACTGGGAAATGGG CAGTTTGGGGAAGTATGGATGGGTACCTGGAATGGAAACACAAAAGTAGCCATAAAGACT CTTAAACCAGGCACAATGTCCCCCGAATCATTCCTTGAGGAAGCGCAGATCATGAAGAAG CTGAAGCACGACAAGCTGGTCCAGCTCTATGCAGTGGTGTCTGAGGAGCCCATCTACATC GTCACCGAGTATATGAACAAAGGAAGTTTACTGGATTTCTTAAAAGATGGAGAAGGAAGA GCTCTGAAATTACCAAATCTTGTGGACATGGCAGCACAGGTGGCTGCAGGAATGGCTTAC ATCGAGCGCATGAATTATATCCATAGAGATCTGCGATCAGCAAACATTCTAGTGGGGAAT GGACTCATATGCAAGATTGCTGACTTCGGATTGGCCCGATTGATAGAAGACAATGAGTAC ACAGCAAGACAAGGTGCAAAGTTCCCCATCAAGTGGACGGCCCCCGAGCGAGCCCTGTAC GGGAGGTTCACAATCAAGTCTGACGTGTGGTCTTTTGGAATCTTACTCACAGAGCTGGTC ACCAAAGGAAGAGTGCCATACCCAGGCATGAACAACCGGGAGGTGCTGGAGCAGGTGGAG CGAGGCTACAGGATGCCCTGCCCGCAGGACTGCCCCATCTCTCTGCATGAGCTCATGATC CACTGCTGGAAAAAGGACCCTGAAGAACGCCCCACTTTTGAGTACTTGCAGAGCTTCCTG GAAGACTACTTTACCGCGACAGAGCCCCAGTACCAACCTGGTGAAAACCTGTAA PF07714 Pkinase_Tyr PF00017 SH2 PF00018 SH3_1 function catalytic activity function protein-tyrosine kinase activity function ATP binding function transferase activity, transferring phosphorus-containing groups function kinase activity function nucleotide binding function protein kinase activity function purine nucleotide binding function adenyl nucleotide binding function binding function transferase activity process physiological process process cellular process process cell communication process metabolism process signal transduction process macromolecule metabolism process biopolymer metabolism process biopolymer modification process protein modification process intracellular signaling cascade process protein amino acid phosphorylation BE0001399 Peptidyl-prolyl cis-trans isomerase F, mitochondrial Human # Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235 unknown Peptidyl-prolyl cis-trans isomerase F, mitochondrial Posttranslational modification, protein turnover, chaperones PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides PPIF 10q22-q23 Mitochondrion; mitochondrial matrix None 9.95 22040.0 Human HUGO Gene Nomenclature Committee (HGNC) HGNC:9259 GenAtlas PPIF GeneCards PPIF GenBank Gene Database M80254 GenBank Protein Database 181274 UniProtKB P30405 UniProt Accession PPIF_HUMAN Cyclophilin F EC 5.2.1.8 Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor PPIase Rotamase >Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor MLALRCGSRWLGLLSVPRSVPLRLPAARACSKGSGDPSSSSSSGNPLVYLDVDANGKPLG RVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSI YGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDV VKKIESFGSKSGRTSKKIVITDCGQLS >624 bp ATGCTGGCGCTGCGCTGCGGCTCCCGCTGGCTCGGCCTGCTCTCCGTCCCGCGCTCCGTG CCGCTGCGCCTCCCCGCGGCCCGCGCCTGCAGCAAGGGCTCCGGCGACCCGTCCTCTTCC TCCTCCTCCGGGAACCCGCTCGTGTACCTGGACGTGGACGCCAACGGGAAGCCGCTCGGC CGCGTGGTGCTGGAGCTGAAGGCAGATGTCGTCCCAAAGACAGCTGAGAACTTCAGAGCC CTGTGCACTGGTGAGAAGGGCTTCGGCTACAAAGGCTCCACCTTCCACAGGGTGATCCCT TCCTTCATGTGCCAGGCGGGCGACTTCACCAACCACAATGGCACAGGCGGGAAGTCCATC TACGGAAGCCGCTTTCCTGACGAGAACTTTACACTGAAGCACGTGGGGCCAGGTGTCCTG TCCATGGCTAATGCTGGTCCTAACACCAACGGCTCCCAGTTCTTCATCTGCACCATAAAG ACAGACTGGTTGGATGGCAAGCATGTTGTGTTCGGTCACGTCAAAGAGGGCATGGACGTC GTGAAGAAAATAGAATCTTTCGGCTCTAAGAGTGGGAGGACATCCAAGAAGATTGTCATC ACAGACTGTGGCCAGTTGAGCTAA PF00160 Pro_isomerase process macromolecule metabolism process protein metabolism process cellular protein metabolism process protein folding process physiological process process metabolism BE0004299 Transcriptional regulator, GntR family Bacillus cereus (strain ATCC 10987) # Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235 unknown Transcriptional regulator, GntR family Transcription BCE_3424 Cytoplasmic None 6.82 27781.9 Bacillus cereus (strain ATCC 10987) GenBank Gene Database AE017194 GenBank Protein Database 42734997 UniProtKB Q734I1 UniProt Accession Q734I1_BACC1 >Transcriptional regulator, GntR family MASGSTQVKYLGIYQKMKQQILDGEYKINEKIPSSPILAEEFGVSVLTIKKALDLLVRDG YIIRRRGSGTVVQDWRQQEKARMIQTLTGTKAVYGSEVESKIIEFTIVGADEIIAEKLGI SVGDFVYKIIRLRIIHSIPTIMEHTWMPIAVIPGVEASVLEESIYSYIQNKLGLKVGTSV VRVKGIRPDDKEKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVITAK SYKEA >1341 bp TTGGAAAACATCTCTGATTTATGGAACAGCGCCTTAAAAGAACTAGAAAAAAAGGTCAGT AAACCAAGCTATGAAACATGGTTAAAATCAACGACCGCACATAATTTAAAGAAAGATGTA TTAACAATTACGGCTCCAAATGAATTCGCCCGCGATTGGCTAGAATCTCATTATTCAGAG CTAATTTCGGAAACACTTTATGATTTAACAGGGGCAAAACTAGCTATTCGCTTTATTATT CCCCAAAGTCAAGCTGAAGAGGAGATCGATCTTCCTCCTTCTAAACCGAATTCAGCACAA GATGATTCTAATCATTTACCACAGAGTATGCTAAATCCAAAATATACGTTTGATACGTTT GTTATTGGCTCTGGTAACCGTTTTGCTCACGCTGCTTCATTGGCCGTAGCCGAAGCGCCA GCTAAAGCATATAATCCCCTCTTTATTTATGGGGGAGTTGGACTTGGAAAGACCCATTTA ATGCATGCAATTGGTCATTATGTAATTGAACATAACCCAAATGCCAAAGTTGTATATTTA TCATCAGAAAAATTTACAAATGAATTTATTAATTCTATTCGTGATAATAAAGCAGTCGAT TTTCGTAATAAATACCGCAATGTAGATGTTTTATTGATAGATGATATTCAATTTTTAGCG GGAAAAGAACAAACTCAAGAAGAGTTTTTCCATACATTCAATGCATTACACGAAGAAAGT AAACAAATTGTAATTTCCAGTGATCGGCCACCAAAAGAAATTCCAACTTTAGAAGATCGT CTTCGTTCTCGCTTTGAATGGGGACTCATTACGGATATTACGCCACCAGATTTAGAAACA CGAATTGCAATTTTGCGCAAAAAAGCAAAGGCTGAAGGACTTGATATACCAAATGAGGTC ATGCTTTATATTGCAAATCAAATCGATTCAAATATTCGTGAACTAGAAGGTGCACTCATC CGAGTTGTAGCTTATTCATCTTTAATTAATAAAGATATTAATGCTGATTTAGCAGCTGAA GCACTTAAAGATATTATTCCAAATTCTAAACCAAAAATTATCTCCATTTATGATATTCAA AAAGCTGTCGGAGATGTTTATCAAGTAAAATTGGAAGATTTCAAGGCGAAAAAGCGAACG AAATCAGTTGCCTTTCCTCGCCAAATTGCAATGTATTTATCACGTGAACTGACAGACTCC TCCTTACCTAAAATAGGTGAAGAATTCGGTGGACGCGATCATACAACCGTTATCCATGCT CATGAAAAAATTTCTAAGCTACTTAAGACGGACACGCAATTACAAAAGCAAGTTGAAGAA ATTAACGATATTTTAAAGTAG PF00392 GntR PF07702 UTRA component cell component intracellular function DNA binding function binding function transcription regulator activity function nucleic acid binding function transcription factor activity process regulation of biological process process regulation of physiological process process regulation of metabolism process regulation of cellular metabolism process regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism process regulation of transcription process regulation of transcription, DNA-dependent BE0004300 ABC transporter, periplasmic substrate-binding protein Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) # Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235 unknown ABC transporter, periplasmic substrate-binding protein Amino acid transport and metabolism SPO2066 None 4.87 67355.2 Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) GenBank Gene Database CP000031 GenBank Protein Database 56676666 UniProtKB Q5LRQ9 UniProt Accession Q5LRQ9_RUEPO >ABC transporter, periplasmic substrate-binding protein MRPDYFRPFRPLTAGIALLLGASFADAESRHAIAMYGAPALPPDFVSLPYANPDAPKGGR VVFGNTGGFDSLNPFAQKGTFPWQMPFWSYESLMGRSWDEPFTLYGLLAESVEVPPDRAW VEFTLREEARFSDGSPVTVEDVIWSYQTLGTEGHLRYRGFWSRIASIEATGPRSLRITFA DEDRELAMLAGLRPILQKAQWEGRSLSEGNIHDIPIGTGPYVVSAYEPGRYVTFARNPDY WGADLGFRRGTMNFDEMRIDFFGDGTVLMEAFKAGELSAIREFNAQKWDSAYDFPAAQRG DVIKTEIAHGKPSGMTGFVINTRRAPFDDWRLREALLLAFNFEFINDTVTGGVMPRITSY FSGTDLAYRPGTASGREAELLAPFAADLPPGTLEGYALPQGDGTARNRTNLRRAAQFLEQ AGFRIEQGQLLGPDGAPLALRFLLRQGDSDMQTVLEIYTRALERLGIAAQIEKVDNAQYT ARVAELDFDLTPFRRDLSLSPGNEQRLYWGSHSAGQPGTRNLMGAASPAIDAMIDRMLAA TTEDELTAATRALDRVLTAGRYVIPIWRFDVGRIAHIRQLRFPPNPPIYGDGPQYMPDVW WYQD >1869 bp GTGAAACATTCGGATTTCGATATTGTCGTGATCGGGGCCGGACATGCCGGCGCCGAGGCT GCACATGCTGCGGCACGCATGGGAATGCGTACTGCCTTGGTTTCCCTGTCCGAACGCGAC ATTGGCGTGATGTCCTGTAACCCGGCTATTGGCGGTTTGGGTAAGGGGCATCTGGTTCGC GAGATCGACGCACTTGACGGGGTCATGGGGCGGGTGGCCGACAAGGCCGGGATTCAATTT CGTCTGCTCAATCGGCGCAAGGGTCCTGCGGTCCAGGGGCCGCGCGCTCAGGCCGATCGC AAGCTCTATCGCCTGGCGATGCAGGAAGAAATGCGCAATCGCCCCGGACTGACCATCGTC GAGGGCGAGGTTACTGATTTTCGAATGCAAGGTGATCGCGTTGCCGGCGTCGTTCTGGCC GATGGGTCCGAGATTGCATCGCAAGCCGTGATCTTGACCTCGGGCACGTTCCTGCGCGGG ATCATTCATATTGGCGATGTTTCGCGCCCCGGTGGGCGGATGGGTGACCGACCTTCAGTT CCGCTTGCCGAAAGGCTGGATGGATTTGCGTTACCGATGGGGCGACTAAAGACCGGAACG CCGCCGCGACTGGACGGACGCACCATAGACTGGTCTATCCTCGAGCGTCAGGACGGGGAT GACGATCCGGTGCTGTTCTCGTTCCTGTCAAAAGGGGCCTATGCGCGTCAGATCGCCTGC GGTATCACGCATACCAACGCCCAGACGCATGAGATCATTCGCAAAAACCTGTCCCGTTCC GCGATGTATGGCGGACATATCGAAGGCGTCGGCCCTCGTTACTGCCCCTCGATCGAGGAC AAAATCGTGCGTTTCGCTGACAAGGATTCGCATCAGATCTTTCTTGAGCCCGAGGGGCTG GAAGATCACACTGTCTATCCGAACGGTATCTCGACCTCGTTGCCGGTCGACGTGCAAGAG GACTATGTCCGTTCGATCCGGGGGCTGGAACAGGTTGAGATCTTGCAGCCCGGTTACGCG ATCGAATACGACTATGTTGATCCCCGCGCGCTCACGTCGCAACTGTCTCTGCCGAATGTT CCGGGCTTGTACCTAGCCGGTCAGATCAATGGAACAACCGGGTATGAAGAGGCTGCGGCG CAGGGAATGGTTGCCGGGTTGAACGCAGCCACCGCGATTTTGGGTCACGAACCGGTCCCC TTCAGTCGTGCCAACAGCTATATCGGTGTGATGATCGACGATCTGACCACACGCGGTGTG GCAGAGCCCTATCGCATGTTCACCTCGCGGGCCGAATTCCGCCTGTCCTTGCGTGCGGAT AACGCGGATCAGCGGCTGACGCCCTTGGGATTGGAATTGGGTTGTGTCGGTGACGAACGG CGCGACGTCTTTGCGCGTAAGGCAGAGAAACTGGCGACAGCCTCGGCGCTGCTCGATCAG AGCAGCTTTAGCCCCAAAGAGATTGCCACAGCTGGTATCACCATCAGTCAGGACGGCAAT CGGAGAAACGGCTTCGCTGTCCTCGCCTTTCCGGACGTCAGGTTTGACGACCTTGTGCCA CTAATCCCGGAACTTGCAGACACCGACGCCGAAACCCGCGCGCAGGTAGAGCGTGATGCG CTTTATGCCAATTACATCGCGCGGCAGGAACGGGATGTTGAGGCGATGAAACGGGATGAG GCGCTGGTCATTCCGATCGACTTCAACTTTTCTGCCCTCGATGGGTTGTCAAATGAGTTG AAGCAAAAACTCACATCCGCGCGACCGGAAAATATCGCGCAGGCCGGGCGTGTTGAGGGG ATGACGCCAGCGGCGCTTGCGCTCATCCTGGCCCGCCTTCGCCGTGGCGACCGAGCACGA AGCGCATGA PF00496 SBP_bac_5 function transporter activity process cellular physiological process process transport process physiological process BE0004301 Transketolase Bacillus anthracis # Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235 unknown Transketolase Carbohydrate transport and metabolism tkt2 None 4.71 72408.7 Bacillus anthracis GeneCards tkt-2 GenBank Gene Database AE016879 GenBank Protein Database 30253517 UniProtKB Q81Y15 UniProt Accession Q81Y15_BACAN >Transketolase MSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTQFMKHNPNNPTWFNRD RFVLSAGHGSMLLYSLLHLSGYDVTMDDLKNFRQWGSKTPGHPEYGHTAGVDATTGPLGQ GIATAVGMAMAERHLAAKYNRDAYNIVDHYTYAICGDGDLMEGVSAEASSLAAHLQLGRL VVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAIAKAIEEAKADEKRP TLIEVRTTIGFGSPNKSGKSASHGSPLGVEETKLTKEAYAWTAEQDFHVAEEVYENFRKT VQDVGETAQAEWNTMLGEYAQAYPELANELQAAMNGLLPEGWEQNLPTYELGSKAATRNS SGAVINAIAESVPSFFGGSADLAGSNKTYMNNEKDFTRDDYSGKNIWYGVREFAMGAAMN GIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIAVGEDGPTHEPIEQL AALRAMPNVSVIRPADGNESVAAWRLALESTNKPTALVLTRQDLPTLEGAKDDTYEKVAK GAYVVSASKKETADVILLATGSEVSLAVEAQKALAVDGVDASVVSMPSMDRFEAQTAEYK ESVLPKAVTKRFAIEMGATFGWHRYVGLEGDVLGIDTFGASAPGEKIMEEYGFTVENVVR KVKEML >1341 bp TTGGAAAACATCTCTGATTTATGGAACAGCGCCTTAAAAGAACTCGAAAAAAAGGTCAGT AAACCAAGTTATGAAACATGGTTAAAATCAACAACCGCACATAATTTAAAGAAAGATGTA TTAACAATTACGGCTCCAAATGAATTCGCCCGTGATTGGTTAGAATCTCATTATTCAGAG CTAATTTCGGAAACACTTTATGATTTAACGGGGGCAAAATTAGCTATTCGCTTTATTATT CCCCAAAGTCAAGCTGAAGAGGAGATTGATCTTCCTCCTGCTAAACCAAATGCAGCACAA GATGATTCTAATCATTTACCACAGAGTATGCTAAACCCAAAATATACGTTTGATACATTT GTTATTGGCTCTGGTAACCGTTTTGCTCACGCTGCTTCATTGGCCGTAGCCGAAGCGCCA GCTAAAGCATATAATCCCCTCTTTATTTATGGGGGAGTTGGACTTGGAAAAACCCATTTA ATGCATGCAATTGGCCATTATGTAATTGAACATAACCCAAATGCCAAAGTTGTATATTTA TCATCAGAAAAATTTACAAATGAATTCATTAATTCTATTCGTGATAATAAAGCGGTCGAT TTTCGTAATAAATACCGCAATGTAGATGTTTTATTGATAGATGATATTCAATTTTTAGCG GGAAAAGAACAAACTCAAGAAGAGTTTTTCCATACATTCAATGCATTACACGAAGAAAGT AAACAAATTGTAATTTCCAGTGATCGGCCACCAAAAGAAATTCCAACTTTAGAAGATCGT CTTCGTTCTCGCTTTGAATGGGGACTCATTACGGATATTACGCCACCAGATTTAGAAACA CGAATTGCGATTTTACGTAAAAAGGCAAAGGCTGAAGGACTTGATATACCAAATGAGGTC ATGCTTTATATCGCAAATCAAATCGATTCAAATATTCGTGAACTAGAAGGTGCACTCATC CGCGTTGTAGCTTATTCATCTTTAATTAACAAGGATATTAATGCTGATTTAGCAGCTGAA GCACTTAAAGATATTATTCCAAATTCTAAACCAAAAATTATCTCCATTTATGATATTCAA AAAGCTGTTGGAGATGTTTATCAAGTAAAATTAGAAGATTTCAAGGCGAAAAAGCGCACA AAGTCAGTTGCCTTTCCTCGCCAAATTGCAATGTATTTGTCACGCGAACTGACAGATTCC TCCTTACCTAAAATAGGTGAAGAATTTGGTGGACGTGATCATACAACCGTTATCCATGCC CATGAAAAAATTTCTAAGCTACTTAAGACGGATACGCAATTACAAAAACAAGTTGAAGAA ATTAACGATATTTTAAAGTAG PF02779 Transket_pyr PF02780 Transketolase_C PF00456 Transketolase_N component cell component intrinsic to membrane component integral to membrane component membrane function transferase activity, transferring aldehyde or ketonic groups function signal transducer activity function transketolase activity function receptor activity function transmembrane receptor activity function G-protein coupled receptor activity function rhodopsin-like receptor activity function catalytic activity function transferase activity process signal transduction process cell surface receptor linked signal transduction process G-protein coupled receptor protein signaling pathway process cellular process process cell communication "
owl:sameAs	drug:EXPT02565

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines2/drugbank_small.nt

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