Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB05014"

Predicate	Value (sorted: default)
rdfs:label	"XL999"
rdf:type	drugbank:drugs
drugbank:description	"XL999 has the potential to provide benefit to patients with lung cancer and acute myelogenous leukemia. XL999 is a new chemical entity that inhibits a spectrum of receptor tyrosine kinases (RTKs) with growth promoting and angiogenic properties, including FGFR 1/3, PDGFRα/β, VEGFR2/KDR, KIT, and FLT3. XL999 also inhibits FLT4 and SRC. XL999 has the potential to prevent tumor growth — both directly by a novel effect on tumor cell proliferation and indirectly through inhibition of the host angiogenic response. XL999 induces a cell-cycle block by a mechanism distinct from those previously identified and exhibits broad antitumor activity in xenograft models. "
drugbank:drugCategory	drugcategory:Antineoplastic Agents

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines2/drugbank_small.nt

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