Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB06209"

PredicateValue (sorted: default)
rdfs:label
"Prasugrel"
rdf:type
drugbank:drugs
drugbank:description
"Prasugrel, a thienopyridine derivative, is a platelet activation and aggregation inhibitor structurally and pharmacologically related to clopidogrel and ticlopidine. Similar to clopidogrel, prasugrel is a prodrug that requires enzymatic transformation in the liver to its active metabolite, R-138727. R-138727 irreversibly binds to P2Y12 type ADP receptors on platelets thus preventing activation of the GPIIb/IIIa receptor complex. As a result, inhibition of ADP-mediated platelet activation and aggregation occurs. Prasugrel was developed by Daiichi Sankyo Co. and is currently marketed in the United States and Canada in cooperation with Eli Lilly and Company for acute coronary syndromes planned for percutaneous coronary intervention (PCI). FDA approved in 2009. "
drugbank:drugCategory
drugcategory:Platelet Aggregation Inhibitors
drugbank:interactsWith
drug:Lansoprazole
drug:Ritonavir
drug:Warfarin
drug:Ketoconazole
drug:Ibuprofen
drug:Ginkgo biloba
owl:sameAs
drug:BE0002180
drug:BE0002363
drug:BE0002638
drug:BE0002793
drug:BE0003536
drug:BE0003549
drug:Lansoprazole
drug:Ritonavir
drug:Warfarin
drug:Ketoconazole
drug:Ibuprofen
drug:Ginkgo biloba
drug:Prasugrel
drug:DBMET00099
drug:DBMET00483
drug:DBSALT000145

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines2/drugbank_small.nt

The resource appears as object in 13 triples

Context graph